Structurally similar to natural extracellular matrix (ECM), hydrogel are three dimensional hydrophilic polymer networks that can swell in aqueous medium while still maintain their three-dimensional (3D) structures. Flexible methods of synthesis and wide range of constituents allow us to incorporate different functionalities into hydrogel and protect biologically active molecules from being impaired. Meanwhile, biochemical and physical cues can also be introduced into hydrogel to mimic the in vivo microenvironment, thus acting as a definitive tissue regeneration template to instruct cell assembly into functional tissues or organs. As such, hydrogels have been the material of choice for many applications in regenerative medicine.

Skin regeneration

Wound healing is one of the most complex biological processes characterized by sequential and delicate coordination of multiple cells, molecular regulators and pathways as well as scaffold synthesis to achieve skin regeneration. Once disturbed, this biological event might leads to unfavorable outcomes with functional and cosmetic defects. Tremendous progress in skin biology and biomaterial science offers the possibility to make the repair transformed into a regenerative process, which holds great potential and values in clinical wound healing management. Hydrogel scaffolds can be engineered to administer many factors that facilitate skin regeneration. Moreover, hydrogel can also be customized according to patients’ situation, which makes them an ideal scaffold to treat cutaneous injuries.

Scarless Skin Regeneration- Are we there yet?

Instead of classical wound repair, our products attenuate scar formation and promote complete skin regeneration during deep wound healing.